Lingyun Xing

Discovery and optimization of tetrahydropyrido[4,3-d]pyrimidine derivatives as novel ATX and EGFR dual inhibitors

Tongfei Jing, Xiuqi Miao, Feng Jiang et al. · Bioorganic & Medicinal Chemistry · 2018 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives

Ming Guo, Daiying Zuo, Jun‐Long Zhang et al. · European Journal of Medicinal Chemistry · 2018 · 26 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Discovery of novel mutant-combating ALK and ROS1 dual inhibitors bearing imidazolidin-2-one moiety with reasonable PK properties

Hongrui Lei, Nan Jiang, Xiuqi Miao et al. · European Journal of Medicinal Chemistry · 2019 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis, biological evaluation and molecular modeling of imidazo[1,2-a]pyridine derivatives as potent antitubulin agents

Jin Liu, Daiying Zuo, Tongfei Jing et al. · Bioorganic & Medicinal Chemistry · 2017 · 18 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Structure-based design of 2,4-diaminopyrimidine derivatives bearing a pyrrolyl group as ALK and ROS1 inhibitors

Jie Wang, Shangfei Wei, Tong Li et al. · New Journal of Chemistry · 2020 · 10 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15