The pore size of mesoporous silica nanoparticles regulates their antigen delivery efficiency

Xiaoyu Hong, Xiaofang Zhong, Guangsheng Du, +6

Science Advances

An aluminum adjuvant-integrated nano-MOF as antigen delivery system to induce strong humoral and cellular immune responses

Xiaofang Zhong, Yunting Zhang, Lu Tan, +7

Journal of Controlled Release

VaccinationNanomedicineCross-protectionAntigen Delivery SystemEngineering +9

Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD

Can Cao, Ximena Barros-Álvarez, Shicheng Zhang, +16

Neuron

Psychoactive DrugPsychiatryBehavioral NeuroscienceAddictionMedicine +12

SARS-CoV-2 variants evolve convergent strategies to remodel the host response

Mehdi Bouhaddou, Ann‐Kathrin Reuschl, Benjamin J. Polacco, +77

Cell

Sars-cov-2 VariantsViral EvolutionViral DynamicMolecular BiologyVirology +5

In-depth Site-specific Analysis of N-glycoproteome in Human Cerebrospinal Fluid and Glycosylation Landscape Changes in Alzheimer's Disease

Zhengwei Chen, Qinying Yu, Qing Yu, +8

Molecular & Cellular Proteomics

De novo design of drug-binding proteins with predictable binding energy and specificity

Lei Lü, Xuxu Gou, Sophia K. Tan, +11

Science

Drug TargetEngineeringMolecular BiologyTuned Interaction EnergiesSmall Molecule-binding Proteins +16

EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis

Xiaojia Huang, Weige Tan, Ziteng Liu, +8

Life Sciences

Tumor BiologyCancer ProliferationMedicineCancer Cell BiologyEif4a3-induced Circzfand6 Promotes +9

Smart combination of aluminum hydroxide and MF59 to induce strong cellular immune responses

Zhengjun Chen, Xinyan Hao, Hairui Wang, +5

Journal of Controlled Release

InflammationAutoimmune DiseaseImmunotoxicologySmart CombinationAluminum Hydroxide +8

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase

Chia‐Wei Hu, Matthew Worth, Dacheng Fan, +9

Nature Chemical Biology

EngineeringBiochemistryBioanalysisGlycobiologyElectrophilic Probes +4

A Mn Al double adjuvant nanovaccine to induce strong humoral and cellular immune responses

Nan Qiao, Hairui Wang, Yanhua Xu, +12

Journal of Controlled Release

InflammationCross-protectionInnate Immune SystemImmunologyStrong Humoral +8