Jingxian Liu

Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations

Jackson Champer, Riona Reeves, Suh Yeon Oh et al. · PLoS Genetics · 2017 · 330 citations · Full text

Engineering, Resistance Alleles, Genetics +17

Reducing resistance allele formation in CRISPR gene drive

Jackson Champer, Jingxian Liu, Suh Yeon Oh et al. · Proceedings of the National Academy of Sciences · 2018 · 309 citations · Full text

Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer

Daniel Cui Zhou, Reyka G. Jayasinghe, Siqi Chen et al. · Nature Genetics · 2022 · 262 citations · Full text

A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population

Jackson Champer, Emily Yang, Esther Lee et al. · Proceedings of the National Academy of Sciences · 2020 · 134 citations · Full text

Tumour evolution and microenvironment interactions in 2D and 3D space

Chia-Kuei Mo, Jingxian Liu, Siqi Chen et al. · Nature · 2024 · 101 citations · Full text