Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine

Giuseppina Martella, Annalisa Tassone, Giuseppe Sciamanna, +11

Brain

NeurotransmitterNeurotransmissionHuman DystoniaBidirectional Synaptic PlasticityDyt1 Dystonia +14

Cholinergic Dysfunction Alters Synaptic Integration between Thalamostriatal and Corticostriatal Inputs in DYT1 Dystonia

Giuseppe Sciamanna, Annalisa Tassone, Georgia Mandolesi, +8

Journal of Neuroscience

Synaptic TransmissionNeurotransmitterNeurotransmissionNeural MechanismNeurodynamics +17

Early structural and functional plasticity alterations in a susceptibility period of DYT1 dystonia mouse striatum

Marta Maltese, Jennifer Stanic, Annalisa Tassone, +9

eLife

Anticholinergic drugs rescue synaptic plasticity in DYT1 dystonia: Role of M₁ muscarinic receptors

Marta Maltese, Giuseppina Martella, Graziella Madeo, +8

Movement Disorders

Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia

Francesco Napolitano, Massimo Pasqualetti, Alessandro Usiello, +14

Neurobiology of Disease

Molecular PharmacologyFunctional SelectivityMedicinePhysiologyNeurotransmitter +5

Impaired striatal D2 receptor function leads to enhanced GABA transmission in a mouse model of DYT1 dystonia

Giuseppe Sciamanna, Paola Bonsi, Annalisa Tassone, +8

Neurobiology of Disease

Gaba TransmissionNeurotransmitterNeuropharmacologyDyt1 DystoniaNeuroscience +6

Regional specificity of synaptic plasticity deficits in a knock-in mouse model of DYT1 dystonia

Giuseppina Martella, Marta Maltese, Robert Nisticò, +10

Neurobiology of Disease

Synaptic PlasticitySynaptic Plasticity DeficitsDevelopmental BiologyMolecular NeuroscienceNeuroanatomy +11

Developmental Profile of the Aberrant Dopamine D2 Receptor Response in Striatal Cholinergic Interneurons in DYT1 Dystonia

Giuseppe Sciamanna, Annalisa Tassone, Giuseppina Martella, +7

PLoS ONE

Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA

Giuseppe Sciamanna, Robert H. Hollis, Chelsea Ball, +10

Neurobiology of Disease

Neurodegenerative DiseasesCholinergic DysregulationDystonia-associated Protein TorsinaPhysiologyNeurotransmitter +9

Powerful inhibitory action of mu opioid receptors (MOR) on cholinergic interneuron excitability in the dorsal striatum

Giulia Ponterio, Annalisa Tassone, Giuseppe Sciamanna, +4

Neuropharmacology

Cholinergic Interneuron ExcitabilityNeurophysiologyNeuroanatomyMedicineNeuropharmacology +9