Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer Platform

Kenji Kozuka, Ying He, Samantha Koo-McCoy, +13

Stem Cell Reports

Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability

Andrew J. King, Matthew Siegel, Ying He, +28

Science Translational Medicine

Intestinal Inhibition of the Na ⁺ /H ⁺ Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na ⁺ Uptake in Humans

Andrew Spencer, Eric D. Labonté, David P. Rosenbaum, +13

Science Translational Medicine

Dysregulation of Insulin Secretion in Children With Congenital Hyperinsulinism due to Sulfonylurea Receptor Mutations

Adda Grimberg, Robert J. Ferry, Andrea Kelly, +9

Diabetes

Metabolic DisorderInsulin SignalingMetabolic SyndromeKatp Channel ActivityHealth Sciences +15

Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD

Eric D. Labonté, Christopher W. Carreras, Michael R. Leadbetter, +15

Journal of the American Society of Nephrology

NutritionElectrolyte DisorderGastroenterologyOsteoporosisRat Model +19

Acute Insulin Responses to Leucine in Children with the Hyperinsulinism/Hyperammonemia Syndrome

Andrea Kelly, Diva D. Ng, Robert J. Ferry, +4

The Journal of Clinical Endocrinology & Metabolism

Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice

Patricia D. Finn, David Rodríguez, Jill Kohler, +21

American Journal of Physiology-Gastrointestinal and Liver Physiology

Carnitine membrane transporter deficiency: a long-term follow up and OCTN2 mutation in the first documented case of primary carnitine deficiency

Stephen D. Cederbaum, Samantha Koo-McCoy, Ingrid Tein, +6

Molecular Genetics and Metabolism

Inherited Metabolic DiseasePhysiologyPrimary Carnitine DeficiencyMembrane BiologyLong-term Follow +2

Calcium-stimulated insulin secretion in diffuse and focal forms of congenital hyperinsulinism

Robert J. Ferry, Andrea Kelly, Adda Grimberg, +7

The Journal of Pediatrics

Developmental BiologyGrowth HormonePhysiologyDiabetesCongenital Hyperinsulinism +5

Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)

Tao Chen, Nicholas William Reich, Noah Bell, +14

Journal of Medicinal Chemistry