Miyuki Tsumura

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text

Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells

Elissa K. Deenick, Danielle T. Avery, Anna Chan et al. · The Journal of Experimental Medicine · 2013 · 182 citations · Full text

Autoimmune Disease, Immune Cell Development, Distinct Requirements +15

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry, Paul Bastard, Adrian Gervais et al. · Proceedings of the National Academy of Sciences · 2022 · 180 citations · Full text

Ifn Autoantibodies, Immunology, Age Dependent +16

Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection

Shen‐Ying Zhang, Nathaniel E. Clark, Catherine A. Freije et al. · Cell · 2018 · 129 citations · Full text

Viral Replication, Inborn Errors, Molecular Virology +11

Abnormal hematopoiesis and autoimmunity in human subjects with germline IKZF1 mutations

Akihiro Hoshino, Satoshi Okada, Kenichi Yoshida et al. · Journal of Allergy and Clinical Immunology · 2016 · 122 citations · Full text

Immunogenetics, Autoimmune Disease, Immunodeficiencies +13