Brian A. Otter

Activities of antifolate, antiviral, and other drugs in an immunosuppressed rat model of Pneumocystis carinii pneumonia

Peter D. Walzer, J Foy, Paul E. Steele et al. · Antimicrobial Agents and Chemotherapy · 1992 · 67 citations

Pharmacological Study, Antiparasitic Agent, Medicine +13

Synthesis of "9-deazaguanosine" and other new pyrrolo[3,2-d]pyrimidine C-nucleosides

Mu Ill Lim, Wu Yun Ren, Brian A. Otter et al. · The Journal of Organic Chemistry · 1983 · 67 citations

Therapeutic Drug Monitoring, Medicinal Chemistry, Molecular Sciences +15

4-aza-7,9-dideazaadenosine, a new cytotoxic synthetic C-nucleoside analogue of adenosine

Shirish A. Patil, Brian A. Otter, Robert S. Klein · Tetrahedron Letters · 1994 · 53 citations

Bioorganic Chemistry, Biochemistry, Medicine +6

Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase.

Edward L. Schwartz, Nicole Baptiste, Carolyn J. O'Connor et al. · PubMed · 1994 · 52 citations

Medicinal Chemistry, Colon Carcinoma Cells, Chemoprevention Strategy +15

A novel stereospecific radical cyclization of 2′,3′-O-isopropylideneuridine and -adenosine 5′-aldehyde to the corresponding 6,5′-cyclodihydrouridine and 8,5′-cycloadenosine derivatives

Tomokazu Sugawara, Brian A. Otter, Tohru Ueda · Tetrahedron Letters · 1988 · 48 citations

8,5′-Cycloadenosine Derivatives, Bioorganic Chemistry, Derivatives +6