Pétur Snæbjörnsson

Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers

Myriam Chalabi, Lorenzo F. Fanchi, Krijn K. Dijkstra et al. · Nature Medicine · 2020 · 1.3K citations · Full text

Neoadjuvant Immunotherapy, Tumor Immunology, Cancer Immunosurveillance +11

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

Krijn K. Dijkstra, Chiara M. Cattaneo, Fleur Weeber et al. · Cell · 2018 · 1K citations · Full text

Tumor-reactive T Cells, Cell Therapy, Cancer Immunosurveillance +10

Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients

Salo Ooft, Fleur Weeber, Krijn K. Dijkstra et al. · Science Translational Medicine · 2019 · 769 citations

Gastrointestinal Oncology, Pdo Test, Medicine +9

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers

Wouter Scheper, Sander Kelderman, Lorenzo F. Fanchi et al. · Nature Medicine · 2018 · 556 citations

Cancer Immunosurveillance, Intratumoral Tcr Repertoire, Medicine +11

Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial

Charlotte E.L. Klaver, D D Wisselink, Cornelis J.A. Punt et al. · ˜The œLancet. Gastroenterology & hepatology · 2019 · 312 citations · Full text

Health Sciences, Gastrointestinal Oncology, Medicine +8