Concepedia
Statistics
Publications
13
Citations
507
H-Index
Active since
2010
Affiliations
University of Louisville(Current)
University at Buffalo, State University of New York
University of Virginia
Christine E. Schaner Tooley is an author at University of Louisville specializing in medicine, epigenetics, and cell biology.
Top concepts
MedicineEpigeneticsCell BiologyGeneticsChromatinGene ExpressionTranscriptional RegulationEpigenomicsBiochemistryDna Methylation
Publications per year
2010–2022
NRMT is an α-N-methyltransferase that methylates RCC1 and retinoblastoma protein
Christine E. Schaner Tooley, Janusz J. Petkowski, Tara L. Muratore‐Schroeder et al. · Nature · 2010 · 132 citations · Full text
Chromatin, Transcriptional Regulation, Cell Regulation +9
Substrate Specificity of Mammalian N-Terminal α-Amino Methyltransferase NRMT
Janusz J. Petkowski, Christine E. Schaner Tooley, Lissa C. Anderson et al. · Biochemistry · 2012 · 61 citations · Full text
Dna Methylation, Molecular Biology, Peptide Science +16
NRMT2 is an N-terminal monomethylase that primes for its homologue NRMT1
Janusz J. Petkowski, Lindsay A. Bonsignore, John G. Tooley et al. · Biochemical Journal · 2013 · 53 citations · Full text
Histone Modifications, Epigenetic Change, Dna Methylation +28
NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging
Lindsay A. Bonsignore, John G. Tooley, Patrick M. Van Hoose et al. · Mechanisms of Ageing and Development · 2015 · 48 citations
Knockout Mouse, Chromatin, Genome Instability +8
Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis
Lindsay A. Bonsignore, Jill Sergesketter Butler, Carolyn M. Klinge et al. · Oncotarget · 2015 · 40 citations · Full text
1–5 of 13