Shannon K. Hughes

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

Ioannis K. Zervantonakis, Shannon K. Hughes, Joseph L. Charest et al. · Proceedings of the National Academy of Sciences · 2012 · 840 citations · Full text

Endothelial Permeability, Engineering, Biological Microenvironments +23

2D protrusion but not motility predicts growth factor–induced cancer cell migration in 3D collagen

Aaron S. Meyer, Shannon K. Hughes, Jennifer E. Kay et al. · The Journal of Cell Biology · 2012 · 95 citations · Full text

Engineering, Cell Proliferation, Biomedical Engineering +17

Mena binds α5 integrin directly and modulates α5β1 function

Stephanie L. Gupton, Daisy Riquelme, Shannon K. Hughes et al. · The Journal of Cell Biology · 2012 · 61 citations · Full text

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena

Shannon K. Hughes, Madeleine J. Oudin, Jenny Tadros et al. · Molecular Biology of the Cell · 2015 · 41 citations · Full text

Molecular Regulation, Tyrosine Kinase, Molecular Biology +21

Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression

Madeleine J. Oudin, Shannon K. Hughes, Nazanin Rohani et al. · Clinical & Experimental Metastasis · 2015 · 29 citations · Full text

Breast Oncology, Breast Tumor Progression, Pro-metastatic Menainv Isoform +8