Concepedia

Christopher Heim

CH

Statistics

Publications

10

Citations

370

H-Index

10

Active since

2016

Affiliations

Max Planck Institute for Developmental Biology(Current)

University of Tübingen

Max Planck Institute for Biology

Togliatti State University

University of Bonn

Christopher Heim is an author at Max Planck Institute for Developmental Biology specializing in ligand binding, drug design, and biochemistry.

ORCID

Publications per year

2016–2023

10

Publications

10

Chemical Ligand Space of Cereblon

Iuliia Boichenko, Kerstin Bär, Silvia Deiss et al. · ACS Omega · 2018 · 66 citations · Full text

, , +15

De-Novo Design of Cereblon (CRBN) Effectors Guided by Natural Hydrolysis Products of Thalidomide Derivatives

Christopher Heim, Dimanthi Pliatsika, Farnoush Mousavizadeh et al. · Journal of Medicinal Chemistry · 2019 · 64 citations · Full text

, , +15

Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon

Christopher Heim, Anna-Katharina Spring, Sören Kirchgäßner et al. · Biochemical and Biophysical Research Communications · 2022 · 50 citations · Full text

, , +3

Leveraging Ligand Affinity and Properties: Discovery of Novel Benzamide-Type Cereblon Binders for the Design of PROTACs

Christian Steinebach, Aleša Bricelj, Arunima Murgai et al. · Journal of Medicinal Chemistry · 2023 · 46 citations · Full text

, , +15

Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines

Mikhail Krasavin, Maria Adamchik, Andrey Bubyrev et al. · European Journal of Medicinal Chemistry · 2022 · 34 citations · Full text

, , +15

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