Lynde M. Wangler

Astrocyte immunosenescence and deficits in interleukin 10 signaling in the aged brain disrupt the regulation of microglia following innate immune activation

Shane M. O’Neil, Emma Hans, Starr Jiang et al. · Glia · 2022 · 56 citations

Life Sciences, Immunology, Neuroscience +17

Amplified Gliosis and Interferon-Associated Inflammation in the Aging Brain following Diffuse Traumatic Brain Injury

Lynde M. Wangler, Chelsea E. Bray, Jonathan M. Packer et al. · Journal of Neuroscience · 2022 · 50 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Impaired cortical neuronal homeostasis and cognition after diffuse traumatic brain injury are dependent on microglia and type I interferon responses

Jonathan M. Packer, Chelsea E. Bray, Nicolas B. Beckman et al. · Glia · 2023 · 35 citations · Full text

Life Sciences, Immunology, Neuroscience +17

Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition

Jonathan M. Packer, Samantha G. Giammo, Lynde M. Wangler et al. · Journal of Neuroinflammation · 2025 · 18 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17