Lead induces oxidative stress, DNA damage and alteration of p53, Bax and Bcl-2 expressions in mice

Jin Xu, Lingjun Lian, Chen Wu, +3

Food and Chemical Toxicology

Dna DamageBiochemistryLipid PeroxidationCell DeathLead Identification +9

Altered expression of p53, Bcl-2 and Bax induced by microcystin-LR in vivo and in vitro

Wenyu Fu, Jiaping Chen, Xiumin Wang, +1

Toxicon

Cancer ResearchAltered ExpressionImmunologyCell DeathMedicine +3

Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis

Wenyu Fu, Dmytro V. Vasylyev, Yufei Bi, +23

Nature

14-3-3 epsilon is an intracellular component of TNFbib2 receptor complex and its activation protects against osteoarthritis

Wenyu Fu, Aubryanna Hettinghouse, Yujianan Chen, +13

Annals of the Rheumatic Diseases

TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity

Wenyu Fu, Wenhuo Hu, Young‐Su Yi, +11

Journal of Clinical Investigation

Inflammatory Lung DiseaseImmunologyImmune RegulationRenal InflammationInnate Immunity +18

Microcystin-LR induces cytoskeleton system reorganization through hyperphosphorylation of tau and HSP27 via PP2A inhibition and subsequent activation of the p38 MAPK signaling pathway in neuroendocrine (PC12) cells

Guanmin Meng, Yu Sun, Wenyu Fu, +2

Toxicology

Subsequent ActivationSignal TransductionSignaling PathwayMolecular PathwayCell Signaling +9

Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models

Jianlu Wei, Wenyu Fu, Yuanjing Ding, +4

Arthritis Research & Therapy

Foxo4‐ and Stat3‐dependent IL‐10 production by progranulin in regulatory T cells restrains inflammatory arthritis

Wenyu Fu, Wenhuo Hu, Lei Shi, +3

The FASEB Journal

Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis

Ronghan Liu, Yuehong Chen, Wenyu Fu, +11

Annals of the Rheumatic Diseases

Production of reactive oxygen species and 8-hydroxy-2′deoxyguanosine in KB cells co-exposed to benzo[a]pyrene and UV-A radiation

Xiaowei Zhang, Rudolf S.S. Wu, Wenyu Fu, +2

Chemosphere

BiochemistryPhotochemistryMedicinePhototoxicityOrganic Chemistry +10