Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells

Arnav Moudgil, Michael Wilkinson, Xuhua Chen, +10

Cell

Functional GenomicsSingle Cell SequencingMedicineGeneticsGene Regulation +8

Cellular states are coupled to genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma

Sidharth V. Puram, Michael Mints, Ananya Pal, +24

Nature Genetics

Hpv-related Oropharyngeal CarcinomaViral HeterogeneityPathologyVirologyHead And Neck Squamous Cell Carcinoma +8

Cooperative p16 and p21 action protects female astrocytes from transformation

Najla Kfoury, Tao Sun, Kwanha Yu, +10

Acta Neuropathologica Communications

Role of WNT7B-induced Noncanonical Pathway in Advanced Prostate Cancer

Dali Zheng, Keith F. Decker, Tianhua Zhou, +7

Molecular Cancer Research

Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma

Najla Kfoury, Zongtai Qi, Briana C. Prager, +10

Proceedings of the National Academy of Sciences

Neuro-oncologyBrd4-bound EnhancersGliomaTumor HeterogeneityMedicine +11

Single-Cell Deconvolution of Head and Neck Squamous Cell Carcinoma

Zongtai Qi, Yating Liu, Michael Mints, +12

Cancers

An optimized, broadly applicable<i>piggyBac</i>transposon induction system

Zongtai Qi, Michael Wilkinson, Xuhua Chen, +3

Nucleic Acids Research

Signal TransductionProtein ExpressionNatural SciencesGenetic EngineeringGene Regulation +13

Redesign of the monomer–monomer interface of Cre recombinase yields an obligate heterotetrameric complex

Chi Zhang, Connie A. Myers, Zongtai Qi, +3

Nucleic Acids Research

EngineeringProtein AssemblyMonomer–monomer InterfaceMolecular BiologyChemical Biology +14

Digital analysis of the expression levels of multiple colorectal cancer-related genes by multiplexed digital-PCR coupled with hydrogel bead-array

Zongtai Qi, Yinjiao Ma, Lili Deng, +4

The Analyst

EngineeringDna MicroarraysHydrogel Bead-arrayCrc PatientsMolecular Biology +30

Self-reporting transposons enable simultaneous readout of gene expression and transcription factor binding in single cells

Arnav Moudgil, Michael Wilkinson, Xuhua Chen, +8