The Spatial and Cell-Type Distribution of SARS-CoV-2 Receptor ACE2 in the Human and Mouse Brains

Rongrong Chen, Keer Wang, Jie Yu, +5

Frontiers in Neurology

NeurovirologyMedicinePhysiologyImmunologySpatial Distribution +13

The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in human and mouse brain

Rongrong Chen, Keer Wang, Jie Yu, +5

NeurophysiologyNeurovirologyImmunologySpatial DistributionSpatial Distribution Analysis +12

Succinate accumulation induces mitochondrial reactive oxygen species generation and promotes status epilepticus in the kainic acid rat model

Yurong Zhang, Mengdi Zhang, Jie Yu, +6

Redox Biology

Structural elucidation of an active polysaccharide from Radix Puerariae lobatae and its protection against acute alcoholic liver disease

Wen Cao, Jianping Wu, Xinya Zhao, +8

Carbohydrate Polymers

Radix Puerariae LobataeBiochemistryStructural ElucidationMedicineGlycobiology +5

Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of <i>Plasmodium falciparum</i> (<i>Pf</i>NDH2) with Small Molecule To Eliminate Drug-Resistant Malaria

Yiqing Yang, You Yu, Xiaolu Li, +8

Journal of Medicinal Chemistry

Drug TargetAldo-keto ReductaseMalariaMolecular BiologyPlasmodium Falciparum +14

Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile Seizures

Yushan Wan, Bo Feng, Yi You, +7

Cell Reports

Structural basis for substrate specificity of an amino acid ABC transporter

Jie Yu, Jingpeng Ge, Johanna Heuveling, +2

Proceedings of the National Academy of Sciences

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N- and T-type calcium channels

Shreya S. Bellampalli, Yingshi Ji, Aubin Moutal, +15

Pain

Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents

Song Cai, Aubin Moutal, Jie Yu, +22

Science Translational Medicine

Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission

Jie Yu, Aubin Moutal, Angie Dorame, +7

Molecular Neurobiology

Molecular NeuroscienceMolecular PhysiologyHealth SciencesSynaptic TransmissionPhysiology +7