Chromatin Accessibility Dynamics during iPSC Reprogramming

Dongwei Li, Jing Liu, Xuejie Yang, +14

Cell stem cell

ChromatinChromatin StructureChromatin RemodelingNatural SciencesGenetics +7

The Ubiquinone-binding Site of the Saccharomyces cerevisiae Succinate-Ubiquinone Oxidoreductase Is a Source of Superoxide

Jing Guo, Bernard D. Lemire

Journal of Biological Chemistry

Reductive StressYeast Sdh2p SubunitBiosynthesisBiochemistryMitochondrial Function +12

Primate gastrulation and early organogenesis at single-cell resolution

Jinglei Zhai, Jing Guo, Haifeng Wan, +14

Nature

Spatial-ID: a cell typing method for spatially resolved transcriptomics via transfer learning and spatial embedding

Rongbo Shen, Lin Liu, Zihan Wu, +14

Nature Communications

EngineeringSpatial EmbeddingGeneticsTranscriptomics TechnologySpatial Omics +21

A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell–derived kidney model for drug discovery

Cecilia Boreström, Anna Jonebring, Jing Guo, +12

Kidney International

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Jdp2-Jhdm1b-Mkk6-Glis1-Nanog-Essrb-Sall4

Bo Wang, Linlin Wu, Dongwei Li, +23

Cell Reports

Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3

Qi Yang, Jielin Tang, Rongjuan Pei, +12

Journal of Molecular Cell Biology

BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling

Shengyong Yu, Chunhua Zhou, Shangtao Cao, +25

Nature Cell Biology

ChromatinInduced Pluripotent Stem CellDevelopmental BiologyBmp4 ResetsMedicine +6

SS18 regulates pluripotent-somatic transition through phase separation

Junqi Kuang, Ziwei Zhai, Pengli Li, +25

Nature Communications

Abnormal lactate metabolism is linked to albuminuria and kidney injury in diabetic nephropathy

Kengo Azushima, Jean‐Paul Kovalik, Takahiro Yamaji, +11

Kidney International

Glomerular DiseaseUrologyRenal DiseaseAbnormal Lactate MetabolismRenal Function +9