AMINO-METHYL-CYCLOHEXANE-CARBOXYLIC ACID: AMCHA

Shosuke Okamoto, U Okamoto

The Keio Journal of Medicine

Organic ChemistryPharmacotherapyExperimental PharmacologyThrombosisFibrinolytic System +14

AN ACTIVE STEREO-ISOMER (TRANS-FORM) OF AMCHA AND ITS ANTIFIBRINOLYTIC (ANTI-PLASMINIC) ACTION IN VITRO AND IN VIVO

Shosuke Okamoto, Shoichi Sato, Yumiko Takada, +1

The Keio Journal of Medicine

Medicinal ChemistryBiochemistryNatural SciencesMedicineStereoselective Synthesis +4

SYNTHETIC INHIBITORS OF FIBRINOLYSIS: IN VITRO AND IN VIVO MODE OF ACTION

Shosuke Okamoto, Susumu Oshiba, H Mihara, +1

Annals of the New York Academy of Sciences

ThrombosisMedicinal ChemistryBiochemistryMedicineNatural Sciences +6

A SUPPRESSING EFFECT OF ε-AMINO-N-CAPROIC ACID ON THE BLEEDING OF DOGS, PRODUCED WITH THE ACTIVATION OF PLASMIN IN THE CIRCULATORY BLOOD

Shosuke Okamoto, Tetsuo Nakajima, U Okamoto, +5

The Keio Journal of Medicine

Animal PhysiologyVeterinary PhysiologyMedicinePhysiologyHematology +7

Development of Potent and Selective Plasmin and Plasma Kallikrein Inhibitors and Studies on the Structure-Activity Relationship.

Yoshio Okada, Yuko Tsuda, Mayako Tada, +4

Chemical and Pharmaceutical Bulletin

Synthesis of chromogenic substrates specific for human spleen fibrinolytic proteinase (SFP) and human leukocyte elastase (LE).

Yoshio Okada, Yuko Tsuda, Akio Hirata, +2

Chemical and Pharmaceutical Bulletin

Human Leukocyte ElastaseMolecular BiologyProtein PurificationProtein ExpressionBioanalysis +15

Plasminogen-Activator in Human Early Milk: Its Partial Purification and Characterization

U Okamoto, Noboru Horie, Y Nagamatsu, +1

Thrombosis and Haemostasis

Pharmaceutical ScienceProtein PurificationFood ChemistryHuman LactationLactation +18

Human Leukocyte Elastase-Like Proteinase Purified by Affinity Chromatography with Suc-L-Tyr-D-Leu-D-Val-pNA, and Its Identification with Human Spleen Fibrinolytic Proteinase

Y Nagamatsu, U Okamoto, Yuko Tsuda, +1

Thrombosis and Haemostasis

Protein ChemistryAffinity ChromatographyElastase-like ProteinaseProtein ExpressionBiochemistry +13

Development of Active Center-Directed Plasmin and Plasma Kallikrein Inhibitors and Studies on the Structure-Inhibitory Activity Relationship.

Naoki Teno, Keiko Wanaka, Y Okada, +4

Chemical and Pharmaceutical Bulletin

Pharmaceutical SciencePharmacotherapyChemical BiologyPharmaceutical ChemistryMolecular Pharmacology +15

Development of plasma kallikrein selective inhibitors

Yoshio Okada, Yuko Tsuda, Mayako Tada, +4

Biopolymers

Medicinal ChemistryPharmaceutical ScienceBioorganic ChemistryBiochemistryMedicine +11