Kevin J. Williams

Sterol regulatory element–binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

Yoko Kidani, Heidi Elsaesser, M. Benjamin Hock et al. · Nature Immunology · 2013 · 531 citations · Full text

Lipid Synthesis, Immune Cell Development, Metabolic Programming +12

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling

Autumn G. York, Kevin J. Williams, Joseph P. Argus et al. · Cell · 2015 · 435 citations · Full text

Signal Transduction, Oxysterol, Biochemistry +9

FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption

Bethan L. Clifford, Leslie R. Sedgeman, Kevin J. Williams et al. · Cell Metabolism · 2021 · 413 citations · Full text

Inflammation, Lipid Synthesis, Biochemistry +10

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

Trevor Siggers, Anne B. Chang, Ana Teixeira et al. · Nature Immunology · 2011 · 224 citations · Full text

Transcriptional Regulation, Dimer-specific Gene Regulation, Molecular Regulation +12

Dynamic lipidome alterations associated with human health, disease and ageing

Daniel Hornburg, Si Wu, Mahdi Moqri et al. · Nature Metabolism · 2023 · 202 citations · Full text