Emmanuelle Laffly

High-Affinity, Human Antibody-Like Antibody Fragment (Single-Chain Variable Fragment) Neutralizing the Lethal Factor (LF) of <i>Bacillus anthracis</i> by Inhibiting Protective Antigen-LF Complex Formation

Thibaut Pelat, Michael Hust, Emmanuelle Laffly et al. · Antimicrobial Agents and Chemotherapy · 2007 · 105 citations · Full text

Microbial Pathogens, Single-chain Variable Fragment, Laboratory Immunology +21

Selection of a Macaque Fab with Framework Regions Like Those in Humans, High Affinity, and Ability To Neutralize the Protective Antigen (PA) of <i>Bacillus anthracis</i> by Binding to the Segment of PA between Residues 686 and 694

Emmanuelle Laffly, Ludivine Danjou, Florence Condemine et al. · Antimicrobial Agents and Chemotherapy · 2005 · 57 citations · Full text

Macaque Fab, Microbial Pathogens, Bacteriology +25

Monoclonal and recombinant antibodies, 30 years after …

Emmanuelle Laffly, Régis Sodoyer · Human Antibodies · 2006 · 43 citations

A high-affinity macaque antibody Fab with human-like framework regions obtained from a small phage display immune library

Stéphanie Chassagne, Emmanuelle Laffly, Emmanuel Drouet et al. · Molecular Immunology · 2004 · 42 citations

Vaccination, Medicine, Immunology +7

Improvement of an Antibody Neutralizing the Anthrax Toxin by Simultaneous Mutagenesis of Its Six Hypervariable Loops

Emmanuelle Laffly, Thibaut Pelat, Frédéric Cédrone et al. · Journal of Molecular Biology · 2008 · 30 citations

Anthrax Toxin, Health Sciences, Immunology +10