Zhongcheng Cao

Multitarget drug design strategy against Alzheimer’s disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties

Yan Li, Xiaoming Qiang, Li Luo et al. · Bioorganic & Medicinal Chemistry · 2016 · 90 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Biochemistry +7

Pyridoxine-resveratrol hybrids Mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer’s disease

Yang Xia, Xiaoming Qiang, Yan Li et al. · Bioorganic Chemistry · 2017 · 81 citations · Full text

Medicinal Chemistry, Neurodegenerative Diseases, Alzheimer's Disease +11

Design, synthesis and biological evaluation of 4′-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease

Ganyuan Xiao, Yan Li, Xiaoming Qiang et al. · Bioorganic & Medicinal Chemistry · 2016 · 69 citations · Full text

4′-Aminochalcone-rivastigmine Hybrids, Medicine, Drug Discovery +8

Design, synthesis and evaluation of 4′-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer’s disease treatment

Zhongcheng Cao, Jie Yang, Rui Xu et al. · Bioorganic & Medicinal Chemistry · 2018 · 61 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, 4′-Oh-flurbiprofen-chalcone Hybrids +8

Flurbiprofen-chalcone hybrid Mannich base derivatives as balanced multifunctional agents against Alzheimer’s disease: Design, synthesis and biological evaluation

Chaoquan Tian, Xiaoming Qiang, Qing Song et al. · Bioorganic Chemistry · 2019 · 57 citations

Combinatorial Chemistry, Derivative (Chemistry), Balanced Multifunctional Agents +6