Kaempferol 7-O-β-D-glucoside isolated from the leaves of Cudrania tricuspidata inhibits LPS-induced expression of pro-inflammatory mediators through inactivation of NF-κB, AP-1, and JAK-STAT in RAW 264.7 macrophages

Seung-Bin Lee, Ji‐Sun Shin, Hee-Soo Han, +3

Chemico-Biological Interactions

Biflorin, Isolated from the Flower Buds of<i>Syzygium aromaticum</i>L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock

Hwi‐Ho Lee, Ji‐Sun Shin, Wooseok Lee, +3

Journal of Natural Products

Fulgidic Acid Isolated from the Rhizomes of &lt;i&gt;Cyperus rotundus&lt;/i&gt; Suppresses LPS-Induced iNOS, COX-2, TNF-α, and IL-6 Expression by AP-1 Inactivation in RAW264.7 Macrophages

Ji‐Sun Shin, Yujin Hong, Hwi‐Ho Lee, +5

Biological and Pharmaceutical Bulletin

Inflammatory Lung DiseaseMicrobial PathogensLung InflammationNitric OxideLipid Peroxidation +21

EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide as a novel anti-inflammatory EGFR inhibitor

Ahmed Elkamhawy, Ahmed H.E. Hassan, Sora Paik, +5

Bioorganic Chemistry

InflammationMedicinal ChemistryAnti-inflammatoryMedicineImmunology +7

Anti-inflammatory potential of Patrineolignan B isolated from Patrinia scabra in LPS-stimulated macrophages via inhibition of NF-κB, AP-1, and JAK/STAT pathways

Hwi‐Ho Lee, Eungyeong Jang, Shinyoung Kang, +7

International Immunopharmacology

InflammationPatrinia ScabraAnti-inflammatoryAnti-inflammatory PotentialMedicine +7

Repurposing mosloflavone/5,6,7-trimethoxyflavone-resveratrol hybrids: Discovery of novel p38-α MAPK inhibitors as potent interceptors of macrophage-dependent production of proinflammatory mediators

Ahmed H.E. Hassan, Sung Yeun Yoo, Kun Won Lee, +10

European Journal of Medicinal Chemistry

InflammationMolecular PharmacologyMedicinal ChemistryMacrophage-dependent ProductionAnti-inflammatory +8

Patriscabrin F from the roots of Patrinia scabra attenuates LPS-induced inflammation by downregulating NF-κB, AP-1, IRF3, and STAT1/3 activation in RAW 264.7 macrophages

Ji‐Sun Shin, Shinyoung Kang, Hwi‐Ho Lee, +4

Phytomedicine

Environmental SignalingImmunologyPathologyInnate ImmunityOxidative Stress +14

The Anti-Proliferative Activity of the Hybrid TMS-TMF-4f Compound Against Human Cervical Cancer Involves Apoptosis Mediated by STAT3 Inactivation

Joo Young Hong, Kyung‐Sook Chung, Ji‐Sun Shin, +8

Cancers

Immunostimulatory Effects of Live Lactobacillus sakei K040706 on the CYP-Induced Immunosuppression Mouse Model

Seo-Yeon Kim, Ji‐Sun Shin, Kyung‐Sook Chung, +9

Nutrients

3ʹ,4ʹ-Dihydroxyflavone mitigates inflammatory responses by inhibiting LPS and TLR4/MD2 interaction

Hwi‐Ho Lee, Ji‐Sun Shin, Kyung‐Sook Chung, +9

Phytomedicine

InflammationCytokineAnti-inflammatoryMedicineImmunology +6