J. Chad Brenner

The mutational landscape of lethal castration-resistant prostate cancer

Catherine S. Grasso, Yi-Mi Wu, Dan R. Robinson et al. · Nature · 2012 · 2.6K citations

Urology, Somatic Variant, Genitourinary Cancer +2

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

Sooryanarayana Varambally, Qi Cao, Ram S. Mani et al. · Science · 2008 · 1.1K citations · Full text

Histone Modifications, Epigenetic Change, Microrna-101 Leads +17

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

John R. Prensner, Matthew K. Iyer, O. Alejandro Balbin et al. · Nature Biotechnology · 2011 · 1K citations · Full text

Engineering, Disease Progression, Unannotated Lincrna +12

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

Jindan Yu, Jianjun Yu, Ram S. Mani et al. · Cancer Cell · 2010 · 844 citations · Full text

Androgen Receptor, Integrated Network, Cancer Genomics +6

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

Jun Liu, Shifeng Pan, Mindy H. Hsieh et al. · Proceedings of the National Academy of Sciences · 2013 · 819 citations · Full text

Wnt Signaling, Tumor Biology, Signaling Pathway +19