Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis

Tamara Muliaditan, Jonathan Caron, Mary Okesola, +14

Nature Communications

Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors

Paris Kosti, James W. Opzoomer, Karen I. Larios-Martinez, +12

Cell Reports Medicine

Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression

James W. Opzoomer, Joanne E. Anstee, Isaac Dean, +14

Science Advances

Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer

Tamara Muliaditan, James W. Opzoomer, Jonathan Caron, +14

Clinical Cancer Research

Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors

Tamara Muliaditan, Leena Halim, Lynsey M. Whilding, +19

Cell Reports Medicine

LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

Joanne E. Anstee, Karen Feehan, James W. Opzoomer, +22

Developmental Cell

Downmodulation of Effector Functions in NK Cells upon Toxoplasma gondii Infection

Misbah Sultana, Ann Du, Berit Carow, +13

Infection and Immunity

Hypoxia-Sensing CAR T-Cells Provide Safety and Efficacy in Treating Solid Tumors

Paris Kosti, James W. Opzoomer, Karen I. Larios-Martinez, +12

Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression

James W. Opzoomer, Joanne E. Anstee, Isaac Dean, +14