Mélanie Frauli

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists

Christof Haffner, Mélanie Frauli, Stephanie D. Topp et al. · The EMBO Journal · 2004 · 72 citations · Full text

Signal Transduction, Molecular Physiology, Reactive Nitrogen Specie +8

Chemical Switch of a Metabotropic Glutamate Receptor 2 Silent Allosteric Modulator into Dual Metabotropic Glutamate Receptor 2/3 Negative/Positive Allosteric Modulators

Stéphan Schann, Stanislas Mayer, Christel Franchet et al. · Journal of Medicinal Chemistry · 2010 · 49 citations · Full text

Bioorganic Chemistry, Synaptic Transmission, Neurotransmitter +20

Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents

Agnieszka Pałucha-Poniewiera, Aleksandra Kłodzińska, Katarzyna Stachowicz et al. · Neuropharmacology · 2008 · 48 citations

Peripheral Administration, Psychiatry, Functional Selectivity +11

Discovery, Structure–Activity Relationship, and Antiparkinsonian Effect of a Potent and Brain-Penetrant Chemical Series of Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4

Delphine Charvin, Vincent Pomel, Millán Ortiz et al. · Journal of Medicinal Chemistry · 2017 · 43 citations · Full text

Among the twenty classical l-amino acids, only glutamate directly activates metabotropic glutamate receptors

Mélanie Frauli, Pascal Neuville, Claire Vol et al. · Neuropharmacology · 2005 · 26 citations

Metabotropic Glutamate Receptors, Biochemistry, Neurophysiology +11