Tautvydas Karvelis

Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes

Mark D. Szczelkun, Maria S. Tikhomirova, Tomas Šinkūnas et al. · Proceedings of the National Academy of Sciences · 2014 · 495 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease

Tautvydas Karvelis, Gytis Druteika, Greta Bigelyte et al. · Nature · 2021 · 357 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

PAM recognition by miniature CRISPR–Cas12f nucleases triggers programmable double-stranded DNA target cleavage

Tautvydas Karvelis, Greta Bigelyte, Joshua K. Young et al. · Nucleic Acids Research · 2020 · 342 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

crRNA and tracrRNA guide Cas9-mediated DNA interference in<i>Streptococcus thermophilus</i>

Tautvydas Karvelis, Giedrius Gasiūnas, Algirdas Mikšys et al. · RNA Biology · 2013 · 240 citations · Full text

Life Sciences, Microbiology, Molecular Biology +13

Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements

Tautvydas Karvelis, Giedrius Gasiūnas, Joshua K. Young et al. · Genome biology · 2015 · 238 citations · Full text

Life Sciences, Biotechnology, Genetics +17