Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site

Takayuki Ohkuri, Akemi Kosaka, Kei Ishibashi, +9

Cancer Immunology Immunotherapy

InflammationIntratumoral AdministrationCytokineCancer ImmunosurveillanceMedicine +10

Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy

Toshihiro Nagato, Takayuki Ohkuri, Kenzo Ohara, +17

Cancer Immunology Immunotherapy

Lymphoid NeoplasiaAutoimmune DiseaseSoluble FormImmunologyTumor Immunity +8

Defining promiscuous MHC class II helper T-cell epitopes for the HER2/neu tumor antigen.

Hiroya Kobayashi, Monique Wood, You Young Song, +2

PubMed

HistocompatibilityImmunologyImmunoeditingPathologyAntigen Processing +18

Direct costimulation of tumor-reactive CTL by helper T cells potentiate their proliferation, survival, and effector function.

Robert Giuntoli, Jun Lü, Hiroya Kobayashi, +2

PubMed

Helper TEffector PhaseT-regulatory CellImmunologyImmune Regulation +16

Expression of Interleukin-9 in Nasal Natural Killer/T-Cell Lymphoma Cell Lines and Patients

Toshihiro Nagato, Hiroya Kobayashi, Kan Kishibe, +10

Clinical Cancer Research

Inhibition of EBV-Induced Lymphoproliferation by CD4+ T Cells Specific for an MHC Class II Promiscuous Epitope

Ryusuke Omiya, Chantal Buteau, Hiroya Kobayashi, +2

The Journal of Immunology

Tumor-reactive T helper lymphocytes recognize a promiscuous MAGE-A3 epitope presented by various major histocompatibility complex class II alleles.

Hiroya Kobayashi, Yongsheng Song, Dave S.�B. Hoon, +2

PubMed

HistocompatibilityPromiscuous Mage-a3 EpitopeImmunologyImmunoeditingPathology +20

Optimization of Peptide Vaccines to Induce Robust Antitumor CD4 T-cell Responses

Takumi Kumai, Sujin Lee, Hyun-Il Cho, +4

Cancer Immunology Research

VaccinationTumor ImmunologyEffective Peptide VaccinesCancer ImmunosurveillanceImmunology +13

Tyrosinase epitope recognized by an HLA-DR-restricted T-cell line from a Vogt-Koyanagi-Harada disease patient

Hiroya Kobayashi, Taku Kokubo, Michinari Takahashi, +5

Immunogenetics

Tyrosinase EpitopeAutoimmune DiseaseImmunodeficienciesPathogenesisImmunology +11

CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase.

Hiroya Kobayashi, Taku Kokubo, Keisuke Sato, +6

PubMed

ImmunologyPeripheral BloodAntigen ProcessingImmunotherapyTyrosinase Peptides +15