Quentin McAfee

A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

Myrna R. Rosenfeld, Xiaobu Ye, Jeffrey G. Supko et al. · Autophagy · 2014 · 512 citations · Full text

Immunology, Cell Death, Pharmacotherapy +23

Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma

Xiao-Hong Ma, Sheng-Fu Piao, Souvik Dey et al. · Journal of Clinical Investigation · 2014 · 451 citations · Full text

Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

Quentin McAfee, Zhihui Zhang, Arabinda Samanta et al. · Proceedings of the National Academy of Sciences · 2012 · 407 citations · Full text

Mitophagy, Single-agent Antitumor Activity, Impair Tumor Growth +21

PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer

Vito W. Rebecca, Michael C. Nicastri, Colin Fennelly et al. · Cancer Discovery · 2018 · 235 citations · Full text

Measurements of Tumor Cell Autophagy Predict Invasiveness, Resistance to Chemotherapy, and Survival in Melanoma

Xiaohong Ma, Shengfu Piao, Dan Wang et al. · Clinical Cancer Research · 2011 · 233 citations · Full text