David Costain

MECHANISM OF THE ANTIDEPRESSANT ACTION OF ELECTROCONVULSIVE THERAPY

A.R Green, David Costain · The Lancet · 1978 · 155 citations

Pharmacy, Pharmacotherapy, Psychiatry +8

β‐ADRENOCEPTOR ANTAGONISTS INHIBIT THE BEHAVIOURAL RESPONSES OF RATS TO INCREASED BRAIN 5‐HYDROXYTRYPTAMINE

David Costain, A.R. Green · British Journal of Pharmacology · 1978 · 74 citations · Full text

Medicine, Neurobiology, Pharmacology +12

Enhanced 5-hydroxytryptamine-mediated behavioural responses in rats following repeated electroconvulsive shock: Relevance to the mechanism of the antidepressive effect of electroconvulsive therapy

David Costain, A. R. Green · Psychopharmacology · 1979 · 64 citations

Medicine, Neuroscience, Pharmacology +13

ELECTROCONVULSIVE THERAPY AND THE BRAIN: EVIDENCE FOR INCREASED DOPAMINE-MEDIATED RESPONSES

David Costain, Michael Gelder, Philip J. Cowen · The Lancet · 1982 · 51 citations

Life Sciences, Neurology, Neuroscience +14

Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions—III the effects of monoamine antagonists and synthesis inhibitors on the ability of electroconvulsive shock to enhance responses

A.R. Green, David Costain, J.F.W. Deakin · Neuropharmacology · 1980 · 44 citations

Medicine, Neuroscience, Pharmacology +15