Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer

Babak Oskouian, Prathap Sooriyakumaran, Alexander D. Borowsky, +5

Proceedings of the National Academy of Sciences

ApoptosisCell DeathCancer BiologyTumor BiologyOxidative Stress +16

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs

Émilie Degagné, Ashok Kumar Pandurangan, Padmavathi Bandhuvula, +11

Journal of Clinical Investigation

InflammationTumor BiologyStat3-activated MicrornasColon CarcinogenesisMedicine +12

The Immune Modulator FTY720 Inhibits Sphingosine-1-phosphate Lyase Activity

Padmavathi Bandhuvula, Yuen Yee Tam, Babak Oskouian, +1

Journal of Biological Chemistry

ImmunologyImmune RegulationSphingosine 1-Phosphate MetabolismWhereas Lyase GeneInflammation +14

Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania

Kai Zhang, Justine Pompey, Fong‐Fu Hsu, +5

The EMBO Journal

BiosynthesisAldehyde DehydrogenaseBiochemistryParasitic ProtozoaSphingolipid Metabolism +3

S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart

Padmavathi Bandhuvula, Norman Honbo, Guanying Wang, +7

American Journal of Physiology-Heart and Circulatory Physiology

Cardiovascular PharmacologyNovel Therapeutic TargetOxidative StressThrombosisIschemia-reperfusion Injury +17

Natural Sphingadienes Inhibit Akt-Dependent Signaling and Prevent Intestinal Tumorigenesis

Henrik Fyrst, Babak Oskouian, Padmavathi Bandhuvula, +5

Cancer Research

Cancer ResearchOncologyChemoprevention StrategyPrevent Intestinal TumorigenesisMedicine +13

A rapid fluorescence assay for sphingosine-1-phosphate lyase enzyme activity

Padmavathi Bandhuvula, Henrik Fyrst, Julie D. Saba

Journal of Lipid Research

Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues

Alexander D. Borowsky, Padmavathi Bandhuvula, Ashok Kumar, +10

Journal of Lipid Research

Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate

Padmavathi Bandhuvula, Zaiguo Li, Robert Bittman, +1

Biochemical and Biophysical Research Communications

Cellular EnzymologyBiochemistryBioanalysisBodipy-labeled SubstrateBiotechnology +1

Sphingosine phosphate lyase regulates myogenic differentiation <i>via</i> S1P receptor‐mediated effects on myogenic microRNA expression

Anabel S. de la Garza-Rodea, Dianna M. Baldwin, Babak Oskouian, +4

The FASEB Journal

GeneticsCellular PhysiologyTranscriptional RegulationCell RegulationSkeletal Muscle +17