Anthony J. Kaye

Synthesis and Antitumor Properties of <i>N</i>-[2-(Dimethylamino)ethyl]carboxamide Derivatives of Fused Tetracyclic Quinolines and Quinoxalines:  A New Class of Putative Topoisomerase Inhibitors

Leslie W. Deady, Anthony J. Kaye, Graeme J. Finlay et al. · Journal of Medicinal Chemistry · 1997 · 120 citations

Engineering, Chemoprevention Strategy, Antiparasitic Agent +19

Synthesis and antitumor activity of some indeno[1,2-b]quinoline-based bis carboxamides

Leslie W. Deady, José Desneves, Anthony J. Kaye et al. · Bioorganic & Medicinal Chemistry · 2000 · 83 citations

Positioning of the Carboxamide Side Chain in 11-Oxo-11H-indeno[1,2-b]quinolinecarboxamide Anticancer Agents: Effects on Cytotoxicity

Leslie W. Deady, José Desneves, Anthony J. Kaye et al. · Bioorganic & Medicinal Chemistry · 2001 · 59 citations

Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA

Leslie W. Deady, José Desneves, Anthony J. Kaye et al. · Bioorganic & Medicinal Chemistry · 1999 · 40 citations

Medicinal Chemistry, Heterocyclic, Biochemistry +10

Synthesis of Substituted Indeno[1,2-b]quinoline-6-carboxamides, [1]benzothieno[3,2-b]quinoline-4-carboxamides and 10H-quindoline-4-carboxamides: Evaluation of Structure–Activity Relationships for Cytotoxicity

Junjie Chen, Leslie W. Deady, José Desneves et al. · Bioorganic & Medicinal Chemistry · 2000 · 36 citations

Derivative (Chemistry), Organic Chemistry, Structure–activity Relationships +3