Charles S. Umbaugh

The Interaction of Polyglutamine Peptides with Lipid Membranes Is Regulated by Flanking Sequences Associated with Huntingtin

Kathleen A. Burke, Karlina J. Kauffman, Charles S. Umbaugh et al. · Journal of Biological Chemistry · 2013 · 104 citations · Full text

Proteinlipid Interaction, Molecular Biology, Cytoskeleton +18

Huntingtin disrupts lipid bilayers in a polyQ-length dependent manner

Kathleen A. Burke, Kaitlin M. Hensal, Charles S. Umbaugh et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2013 · 79 citations

Proteinlipid Interaction, Biochemistry, Natural Sciences +4

Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing

Anna Thrun, Aitor Garzia, Yu Kigoshi-Tansho et al. · Molecular Cell · 2021 · 75 citations · Full text

Protein Function, Signal Transduction, Biochemistry +10

Heat shock factor 1 over-expression protects against exposure of hydrophobic residues on mutant SOD1 and early mortality in a mouse model of amyotrophic lateral sclerosis

Pei-Yi Lin, Sharotka M. Simon, Won Kyun Koh et al. · Molecular Neurodegeneration · 2013 · 44 citations · Full text

Specific Domains of Aβ Facilitate Aggregation on and Association with Lipid Bilayers

Elizabeth A. Yates, Sherry Owens, Michael Lynch et al. · Journal of Molecular Biology · 2013 · 40 citations

Proteinlipid Interaction, Specific Domains, Biochemistry +13