Patricia J. Sime

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

Patricia J. Sime, Frank L. Graham, Karl G. Csaky et al. · Journal of Clinical Investigation · 1997 · 1K citations · Full text

Life Sciences, Cell Biology, Pathobiology +17

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis

Gísli Jenkins, Bethany B. Moore, Rachel C. Chambers et al. · American Journal of Respiratory Cell and Molecular Biology · 2017 · 431 citations · Full text

Medicine, Pharmacology, Clinical Pharmacology +14

Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β

R.M. Kottmann, Ajit A. Kulkarni, Katie Smolnycki et al. · American Journal of Respiratory and Critical Care Medicine · 2012 · 408 citations

Life Sciences, Biochemistry, Pathobiology +13

PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis

Heather A. Burgess, L. Eugene Daugherty, Thomas H. Thatcher et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2005 · 315 citations

Medicine, Molecular Medicine, Pharmacology +16

Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation

Andrew C. Bakker, Fons A. J. van de Loo, Henk M. van Beuningen et al. · Osteoarthritis and Cartilage · 2001 · 294 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +11