Patricia J. Sime

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

Patricia J. Sime, Frank L. Graham, Karl G. Csaky et al. · Journal of Clinical Investigation · 1997 · 1K citations · Full text

Acute Lung Injury, Inflammatory Lung Disease, Lung Inflammation +20

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis

Gísli Jenkins, Bethany B. Moore, Rachel C. Chambers et al. · American Journal of Respiratory Cell and Molecular Biology · 2017 · 404 citations · Full text

Potential Therapies, Antifibrotic Therapy, Inflammatory Lung Disease +20

Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β

R.M. Kottmann, Ajit A. Kulkarni, Katie Smolnycki et al. · American Journal of Respiratory and Critical Care Medicine · 2012 · 390 citations

PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis

Heather A. Burgess, L. Eugene Daugherty, Thomas H. Thatcher et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2005 · 309 citations

Antifibrotic Therapy, Inflammatory Lung Disease, Lung Inflammation +16

Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation

Andrew C. Bakker, Fons A. J. van de Loo, Henk M. van Beuningen et al. · Osteoarthritis and Cartilage · 2001 · 291 citations · Full text

Regenerative Medicine, Mechanobiology, Developmental Biology +10