Analysis of the fate of systemically administered liposomes and implications for their use in drug delivery.

George Poste, Corazon D. Bucana, Avraham Raz, +3

PubMed

EngineeringImmunologyFree LiposomesExtracellular MicrovesiclesBiomedical Engineering +16

Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.

T K Hart, Richard Kirsh, Harma Ellens, +5

Proceedings of the National Academy of Sciences

GlycobiologyImmunologyEnvelope Glycoprotein Gp120Viral Structural ProteinHuman Immunodeficiency Virus +15

Involvement of macrophages in the eradication of established metastases following intravenous injection of liposomes containing macrophage activators.

I. J. Fidler, Z. Barnes, William E. Fogler, +3

PubMed

Macrophage BiologyInflammationMacrophage ActivatorsLung MetastasesIntravenous Injection +13

Design of liposomes to improve delivery of macrophage-augmenting agents to alveolar macrophages.

I. J. Fidler, A. Raz, William E. Fogler, +3

PubMed

EngineeringLung InflammationImmunologyExtracellular MicrovesiclesOptimal Localization +15

Site–Specific (Targeted) Drug Delivery in Cancer Therapy

George Poste, Richard Kirsh

Bio/Technology

Drug TargetingMedicineTargeted Drug DeliveryDrug Delivery SystemsTargeted Therapy +2

Activation of tumoricidal properties in mouse macrophages by lymphokines encapsulated in liposomes.

George Poste, Richard Kirsh, William E. Fogler, +1

PubMed

InflammationTumoricidal PropertiesCell-based Drug DeliveryLiposome-encapsulated MafNormal Macrophages +12

An Emulsion Formulation of Amphotericin B Improves the Therapeutic Index When Treating Systemic Murine Candidiasis

Richard Kirsh, Robert M. Goldstein, Joan B. Tarloff, +5

The Journal of Infectious Diseases

Rapid decay of tumoricidal activity and loss of responsiveness to lymphokines in inflammatory macrophages.

George Poste, Richard Kirsh

PubMed

Immune RegulationImmunologyPathologyCell DeathTumoricidal Activity +15

Morphometric Analysis of Recombinant Soluble CD4-Mediated Release of the Envelope Glycoprotein gp120 from HIV-1

Richard Kirsh, Timothy K. Hart, Harma Ellens, +5

AIDS Research and Human Retroviruses

Human RetrovirusGlycobiologyImmunologyMolecular BiologyVirology +8

Macrophage content of spontaneous metastases at different stages of growth.

Peter J. Bugelski, StevenP. Corwin, S M North, +3

PubMed

ImmunologyPathologyCell ProliferationCancer BiologyTumor Biology +15