SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated, individuals

Simone I. Richardson, Vimbai Sharon Madzorera, Holly Spencer, +22

Cell Host & Microbe

Prior infection with SARS-CoV-2 boosts and broadens Ad26.COV2.S immunogenicity in a variant-dependent manner

Roanne Keeton, Simone I. Richardson, Thandeka Moyo-Gwete, +32

Cell Host & Microbe

Variant-dependent MannerViral PersistencePrior InfectionCovid-19 PandemicViral Pathogenesis +6

SARS-CoV-2 Beta and Delta variants trigger Fc effector function with increased cross-reactivity

Simone I. Richardson, Nelia P. Manamela, Boitumelo M. Motsoeneng, +16

Cell Reports Medicine

Signal TransductionImmunologySars-cov-2 BetaSystems BiologyMedicine +2

Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions

Andrea R. Shiakolas, Kevin J. Kramer, Daniel Wrapp, +28

Cell Reports Medicine

Emergence and phenotypic characterization of C.1.2, a globally detected lineage that rapidly accumulated mutations of concern

Cathrine Scheepers, Josie Everatt, Daniel G. Amoako, +42

GeneticsImmunologyMolecular GeneticsDisease Gene IdentificationGenomics +19

Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineage

Cathrine Scheepers, Josie Everatt, Daniel G. Amoako, +41

Nature Communications

Ad26.COV2.S breakthrough infections induce high titers of neutralizing antibodies against Omicron and other SARS-CoV-2 variants of concern

Dale Kitchin, Simone I. Richardson, Mieke A. van der Mescht, +22

Cell Reports Medicine

HIV Broadly Neutralizing Antibodies Expressed as IgG3 Preserve Neutralization Potency and Show Improved Fc Effector Function

Simone I. Richardson, Frances Ayres, Nelia P. Manamela, +5

Frontiers in Immunology

ImmunodeficienciesImmunologyImmunodominanceImmunotherapeuticsImmune System +18

Durability of ChAdOx1 nCoV-19 (AZD1222) vaccine and hybrid humoral immunity against variants including omicron BA.1 and BA.4 6 months after vaccination (COV005): a post-hoc analysis of a randomised, phase 1b–2a trial

Shabir A. Madhi, Gaurav Kwatra, Simone I. Richardson, +34

The Lancet Infectious Diseases

SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated individuals

Simone I. Richardson, Vimbai Sharon Madzorera, Holly Spencer, +22

VaccinationVaccine DevelopmentImproved Cross-neutralizationOther VocsVaccine Target +12