Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum

Mariangeles Perez de la Cruz Moreno, M. Oth, S. Deferme, +4

Journal of Pharmacy and Pharmacology

Simulated intestinal fluid as transport medium in the Caco-2 cell culture model

F. Ingels, S. Deferme, Éric Destexhe, +3

International Journal of Pharmaceutics

Simulated Intestinal FluidMembrane TransportPhysiologyGastroenterologyTransport Medium +8

Intestinal Absorption Enhancement of the Ester Prodrug Tenofovir Disoproxil Fumarate through Modulation of the Biochemical Barrier by Defined Ester Mixtures

J. Van Gelder, S. Deferme, Lieve Naesens, +4

Drug Metabolism and Disposition

Drug Absorption Studies: In Situ, In Vitro and In Silico Models

S. Deferme, Pieter Annaert, Patrick Augustijns

Pharmaceutical SciencePharmacological StudyMedicineSilico ModelsDrug Absorption +5

Inhibitory effect of fruit extracts on P-glycoproteinrelated efflux carriers: an in-vitro screening

S. Deferme, J. Van Gelder, Patrick Augustijns

Journal of Pharmacy and Pharmacology

Increased Absorption of the Antiviral Ester Prodrug Tenofovir Disoproxil in Rat Ileum by Inhibiting Its Intestinal Metabolism

J. Van Gelder, S. Deferme, Pieter Annaert, +5

Drug Metabolism and Disposition

P-Glycoprotein Attenuating Effect of Human Intestinal Fluid

S. Deferme, Jan Tack, Frank Lammert, +1

Pharmaceutical Research

New bis(SATE) prodrug of AZT 5′‐monophosphate: In vitro anti‐HIV activity, stability, and potential oral absorption

Manijeh Shafiee, S. Deferme, Anne‐Laure Villard, +11

Journal of Pharmaceutical Sciences

Medicinal ChemistryPharmaceutical ScienceMedicineAntiviral Drug DevelopmentNew Bis +10

Sulfasalazine transport in in-vitro, ex-vivo and in-vivo absorption models: contribution of efflux carriers and their modulation by co-administration of synthetic nature-identical fruit extracts

Raf Mols, S. Deferme, Patrick Augustijns

Journal of Pharmacy and Pharmacology

Medicinal ChemistryPharmaceutical ScienceLow Oral BioavailabilityBiochemistryPharmacological Study +12

Apricot Extract Inhibits the P-gp–Mediated Efflux of Talinolol

S. Deferme, Raf Mols, Willy Van Driessche, +1

Journal of Pharmaceutical Sciences

Apricot ExtractMolecular PharmacologyBiochemistryMedicinePhytopharmacology +4