Structure of the TRPV1 ion channel determined by electron cryo-microscopy

Maofu Liao, Erhu Cao, David Julius, +1

Nature

BiophysicsTrpv1 Ion ChannelMolecular BiologyIon ChannelsMedicine +3

TRPV1 structures in distinct conformations reveal activation mechanisms

Erhu Cao, Maofu Liao, Yifan Cheng, +1

Nature

Molecular PhysiologySignal TransductionProtein AssemblyProtein FoldingNatural Sciences +6

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action

Yuan Gao, Erhu Cao, David Julius, +1

Nature

Proteinlipid InteractionSingle Molecule BiophysicsNatural SciencesNanodiscs Reveal MechanismsMolecular Biology +6

Structural and Functional Analysis of the Costimulatory Receptor Programmed Death-1

Xuewu Zhang, Jean-Claude D. Schwartz, Xiaoling Guo, +7

Immunity

Signal TransductionG Protein-coupled ReceptorMedicineCostimulatory ReceptorApoptosis +8

TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

Erhu Cao, Julio F. Cordero-Morales, Beiying Liu, +2

Neuron

Proteinlipid InteractionMolecular PhysiologySignal TransductionBiochemistryMedicine +9

The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs

Peter Shen, Xiaoyong Yang, Paul G. DeCaen, +4

Cell

Proteinlipid InteractionMolecular PhysiologyLipid NanodiscsBiochemistryKidney Research +5

T Cell Immunoglobulin Mucin-3 Crystal Structure Reveals a Galectin-9-Independent Ligand-Binding Surface

Erhu Cao, Xingxing Zang, U.A. Ramagopal, +11

Immunity

Autoimmune DiseaseImmunologyMolecular BiologyImmunologic MechanismAntigen Processing +5

Crystal structure of the complex between programmed death-1 (PD-1) and its ligand PD-L2

Eszter Lázár‐Molnár, Qingrong Yan, Erhu Cao, +3

Proceedings of the National Academy of Sciences

Crystal StructureDrug TargetMurine Pd-1Cell DeathMolecular Biology +18

TRPV1 Channels are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids

Erhu Cao, Julio F. Cordero-Morales, Beiying Liu, +2

Biophysical Journal

Proteinlipid InteractionMolecular PhysiologySignal TransductionBiochemistryMedicine +9

Structure of CD84 provides insight into SLAM family function

Qingrong Yan, V.N. Malashkevich, E.V. Fedorov, +5

Proceedings of the National Academy of Sciences

Slam Family FunctionEngineeringGeometryAdaptive Immune SystemImmunology +25