Chitraa Tangavel

Human intervertebral discs harbour a unique microbiome and dysbiosis determines health and disease

Shanmuganathan Rajasekaran, Dilip Chand Raja Soundararajan, Chitraa Tangavel et al. · European Spine Journal · 2020 · 98 citations

Dysbiosis Determines Health, Dysbiosis, Intervertebral Disc +8

ISSLS PRIZE IN CLINICAL SCIENCE 2017: Is infection the possible initiator of disc disease? An insight from proteomic analysis

Shanmuganathan Rajasekaran, Chitraa Tangavel, Siddharth N. Aiyer et al. · European Spine Journal · 2017 · 68 citations

Degenerative Spine, Intervertebral Disc, Medicine +9

Inflammaging determines health and disease in lumbar discs—evidence from differing proteomic signatures of healthy, aging, and degenerating discs

Shanmuganathan Rajasekaran, Chitraa Tangavel, K. S. Sri Vijay Anand et al. · The Spine Journal · 2019 · 38 citations

Inflammation, Lumbar Spine, Intervertebral Disc +11

Modic changes are associated with activation of intense inflammatory and host defense response pathways – molecular insights from proteomic analysis of human intervertebral discs

Shanmuganathan Rajasekaran, Dilip Chand Raja Soundararajan, Sharon Miracle Nayagam et al. · The Spine Journal · 2021 · 31 citations · Full text

Inflammation, Proteomic Technology, Inflammatory Disease +13

Bacteria in human lumbar discs – subclinical infection or contamination? Metabolomic evidence for colonization, multiplication, and cell-cell cross-talk of bacteria

Shanmuganathan Rajasekaran, Chitraa Tangavel, Gowdaman Vasudevan et al. · The Spine Journal · 2022 · 20 citations

Medical Microbiology, Bacterial Infections, Microbial Disease +8