Shuhei Hosomi

Paneth cells as a site of origin for intestinal inflammation

Timon E. Adolph, Michal Tomczak, Lukas Niederreiter et al. · Nature · 2013 · 711 citations · Full text

Inflammation, Autoimmune Disease, Mucosal Immunology +8

ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells

Lukas Niederreiter, T Fritz, Timon E. Adolph et al. · The Journal of Experimental Medicine · 2013 · 136 citations · Full text

NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis

Shigehiro Itani, Toshio Watanabe, Yuji Nadatani et al. · Scientific Reports · 2016 · 96 citations · Full text

AJM300 (carotegrast methyl), an oral antagonist of α4-integrin, as induction therapy for patients with moderately active ulcerative colitis: a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

Katsuyoshi Matsuoka, Mamoru Watanabe, Toshihide Ohmori et al. · ˜The œLancet. Gastroenterology & hepatology · 2022 · 78 citations

Inflammation, Anti-inflammatory, Gastrointestinal Pharmacology +9

Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis

Shuhei Hosomi, Nobuhide Oshitani, Noriko Kamata et al. · Clinical & Experimental Immunology · 2010 · 66 citations · Full text

Inflammation, Immature Plasma Cells, Autoimmune Disease +11