Jason R.B. Dyck

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

Timothy R. Koves, John R. Ussher, Robert C. Noland et al. · Cell Metabolism · 2008 · 2K citations · Full text

Life Sciences, Cell Biology, Physiology +16

Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin

Morgan D. Fullerton, Sandra Galić, Katarina Marcinko et al. · Nature Medicine · 2013 · 875 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Phosphodiesterase Type 5 Is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility

Jayan Nagendran, Stephen L. Archer, Daniel Soliman et al. · Circulation · 2007 · 528 citations · Full text

Medicine, Cardiology, Pharmacology +17

Increased Hepatic CD36 Expression Contributes to Dyslipidemia Associated With Diet-Induced Obesity

Debby P.Y. Koonen, René L. Jacobs, Maria Febbraio et al. · Diabetes · 2007 · 505 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

Justin D. Crane, Rengasamy Palanivel, Emilio P. Mottillo et al. · Nature Medicine · 2014 · 484 citations · Full text

Life Sciences, Pharmacology, Physiology +16