Zachary R. Crook

Mitochondrial cytochrome oxidase produces nitric oxide under hypoxic conditions: Implications for oxygen sensing and hypoxic signaling in eukaryotes

Pablo R. Castello, Pamela S. David, Travis McClure et al. · Cell Metabolism · 2006 · 488 citations · Full text

Biology, Mitochondrial Function, Biochemistry +11

Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets

Zachary R. Crook, Gregory P. Sevilla, Della Friend et al. · Nature Communications · 2017 · 76 citations · Full text

Peptide Engineering, Molecular Biology, Diverse Scaffold Libraries +17

A TfR-Binding Cystine-Dense Peptide Promotes Blood–Brain Barrier Penetration of Bioactive Molecules

Zachary R. Crook, Emily J. Girard, Gregory P. Sevilla et al. · Journal of Molecular Biology · 2020 · 34 citations · Full text

Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice

Zachary R. Crook, David E. Housman · Proceedings of the National Academy of Sciences · 2012 · 30 citations · Full text

CYpHER: catalytic extracellular targeted protein degradation with high potency and durable effect

Zachary R. Crook, Gregory P. Sevilla, P. G. Young et al. · Nature Communications · 2024 · 14 citations · Full text