A Viral RNA Structural Element Alters Host Recognition of Nonself RNA

Jennifer Hyde, Christina L. Gardner, Taishi Kimura, +10

Science

A Mouse Model for Studying Viscerotropic Disease Caused by Yellow Fever Virus Infection

Kathryn C. Meier, Christina L. Gardner, Mikhail V. Khoretonenko, +2

PLoS Pathogens

Viral ImmunityViral PathogenesisImmunologyVirus TransmissionVector-borne Pathogen +14

Stable, High-Level Expression of Reporter Proteins from Improved Alphavirus Expression Vectors To Track Replication and Dissemination during Encephalitic and Arthritogenic Disease

Chengqun Sun, Christina L. Gardner, Alan M. Watson, +2

Journal of Virology

Eastern and Venezuelan Equine Encephalitis Viruses Differ in Their Ability To Infect Dendritic Cells and Macrophages: Impact of Altered Cell Tropism on Pathogenesis

Christina L. Gardner, Crystal W. Burke, Mulu Z. Tesfay, +3

Journal of Virology

Viral PathogenesisImmunologyPathologyTheir AbilityImmunotherapy +16

Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence

Christina L. Gardner, Gregory D. Ebel, Kate D. Ryman, +1

Proceedings of the National Academy of Sciences

Molecular VirologyPromotes NeurovirulenceNeurovirologyMedicinePathogenesis +11

Interferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181/25 vaccine candidate

Christina L. Gardner, Crystal W. Burke, Stephen Higgs, +2

Virology

Autoimmune DiseaseViral PathogenesisImmunologyWild-type Chikungunya VirusVirology +7

Deliberate Attenuation of Chikungunya Virus by Adaptation to Heparan Sulfate-Dependent Infectivity: A Model for Rational Arboviral Vaccine Design

Christina L. Gardner, Jozef Hritz, Chengqun Sun, +6

PLoS neglected tropical diseases

Deliberate AttenuationViral PathogenesisImmunologyViral Structural ProteinVirus Transmission +17

Heparan Sulfate Binding Can Contribute to the Neurovirulence of Neuroadapted and Nonneuroadapted Sindbis Viruses

Kate D. Ryman, Christina L. Gardner, Crystal W. Burke, +3

Journal of Virology

Virus StructureMolecular VirologyNonneuroadapted Sindbis VirusesNeurovirologyPathogenesis +12

Similarities and Differences in Antagonism of Neuron Alpha/Beta Interferon Responses by Venezuelan Equine Encephalitis and Sindbis Alphaviruses

Jun Yin, Christina L. Gardner, Crystal W. Burke, +2

Journal of Virology

Veev ReplicationViral PathogenesisImmunologyVirus TransmissionSindbis Alphaviruses +14

Freed-amino acids in human cerebrospinal fluid of alzheimer disease, multiple sclerosis, and healthy control subjects

G. H. Fisher, Leonard Petrucelli, Christina L. Gardner, +7

Molecular and Chemical Neuropathology

Alzheimer's DiseaseCerebrospinal FluidDementiaNeurochemical BiomarkersFreed-amino Acids +9