Joshua H. Butler

Biological Studies and Target Engagement of the 2-<i>C</i>-Methyl-<scp>d</scp>-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1<i>R</i>,3<i>S</i>)-MMV008138 and Analogs

Maryam Ghavami, Emilio F. Merino, Zhong‐Ke Yao et al. · ACS Infectious Diseases · 2017 · 47 citations

Trichloranoids A–D, antimalarial sesquiterpenoid trimers from <i>Chloranthus spicatus</i>

Jun‐Su Zhou, Qun‐Fang Liu, Flávia M. Zimbres et al. · Organic Chemistry Frontiers · 2021 · 45 citations

Biology, Medicinal Chemistry, Biosynthesis +13

Picomolar antimalarial agent from a Chinese medicinal plant

Bin Zhou, Flávia M. Zimbres, Joshua H. Butler et al. · Science China Chemistry · 2021 · 39 citations

Medicinal Chemistry, Chinese Medicinal Plant, Antiparasitic Agent +6

Malaria Box-Inspired Discovery of <i>N</i>-Aminoalkyl-β-carboline-3-carboxamides, a Novel Orally Active Class of Antimalarials

Jopaul Mathew, Sha Ding, Kevin A. Kunz et al. · ACS Medicinal Chemistry Letters · 2022 · 18 citations · Full text

Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a <i>Plasmodium falciparum</i> Esterase

Joshua H. Butler, Rodrigo P. Baptista, Ana Lisa Valenciano et al. · ACS Infectious Diseases · 2020 · 17 citations · Full text