Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

Gi-Bang Koo, Michael K. Morgan, Da‐Gyum Lee, +19

Cell Research

Rip3 ExpressionOncologyMethylation-dependent LossOncogenic AgentMedicine +7

Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia

Krzysztof Mrózek, Guido Marcucci, Deedra Nicolet, +18

Journal of Clinical Oncology

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

Klaus H. Metzeler, Heiko Becker, Kati Maharry, +18

Blood

<i>RUNX1</i> Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures

Jason H. Mendler, Kati Maharry, Michael D. Radmacher, +19

Journal of Clinical Oncology

Age-Related Prognostic Impact of Different Types of <i>DNMT3A</i> Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia

Guido Marcucci, Klaus H. Metzeler, Sebastian Schwind, +18

Journal of Clinical Oncology

Expression and prognostic impact of lncRNAs in acute myeloid leukemia

Ramiro Garzon, Stefano Volinia, Dimitrios Papaioannou, +21

Proceedings of the National Academy of Sciences

Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: <i>miR-155</i> Upregulation Independently Identifies High-Risk Patients

Guido Marcucci, Kati Maharry, Klaus H. Metzeler, +17

Journal of Clinical Oncology

Epigenetics Meets Genetics in Acute Myeloid Leukemia: Clinical Impact of a Novel Seven-Gene Score

Guido Marcucci, Pearlly S. Yan, Kati Maharry, +28

Journal of Clinical Oncology

The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia

Dimitrios Papaioannou, Andreas Petri, Oliver M. Dovey, +30

Nature Communications

An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia

Audrey Lasry, Bettina Nadorp, Maarten Fornerod, +19

Nature Cancer

InflammationHematological MalignancyImmune EvasionInflammatory State RemodelsMixed-phenotype Acute Leukemia +10