Origin and T Cell Receptor Diversity of Foxp3+CD4+CD25+ T Cells

Rafał Pacholczyk, Hanna Ignatowicz, Piotr Kraj, +1

Immunity

Autoimmune DiseaseLymphocyte DevelopmentT-regulatory CellImmunologyAutoimmunity +8

Nonself-Antigens Are the Cognate Specificities of Foxp3+ Regulatory T Cells

Rafał Pacholczyk, Joanna Kern, Nagendra Singh, +3

Immunity

ImmunogeneticsAutoimmune DiseaseMedicineT-regulatory CellImmunology +6

Activation of p53 in Immature Myeloid Precursor Cells Controls Differentiation into Ly6c+CD103+ Monocytic Antigen-Presenting Cells in Tumors

Madhav Sharma, Paulo C. Rodrı́guez, Brent H. Koehn, +16

Immunity

Hematological MalignancyImmunologyMyelopoiesisMedicineCell Biology +3

T Cells Can Be Activated by Peptides That Are Unrelated in Sequence to Their Selecting Peptide

Leszek Ignatowicz, William A. Rees, Rafał Pacholczyk, +4

Immunity

Signal TransductionT CellsT-regulatory CellSelecting PeptideImmunology +8

Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease <i>in vivo</i>

Mahmoud Elashiry, Mohamed Mohamed Elashiry, Ranya Elsayed, +14

Journal of Extracellular Vesicles

Peptide Specificity of Thymic Selection of CD4+CD25+ T Cells

Rafał Pacholczyk, Piotr Kraj, Leszek Ignatowicz

The Journal of Immunology

Systems BiologyAutoimmune DiseaseLymphocyte DevelopmentT CellsT-regulatory Cell +11

A Tryptophan-Deficient Diet Induces Gut Microbiota Dysbiosis and Increases Systemic Inflammation in Aged Mice

Ibrahim Yusufu, Kehong Ding, Kathryn E. Smith, +9

International Journal of Molecular Sciences

<i>Tie2cre</i> -induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

Li Zhou, Kook-Heon Seo, Hong-Zhi He, +7

Proceedings of the National Academy of Sciences

ImmunologyImmune RegulationCell DeathImmunologic MechanismInkt Cells +19

Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma

Yousef Zakharia, Robert R. McWilliams, Olivier Rixe, +17

Journal for ImmunoTherapy of Cancer

Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity

Madhav Sharma, Rafał Pacholczyk, Huidong Shi, +15

Immunity

Cancer ImmunosurveillanceImmunologyTumor ImmunityAutoimmunityT Cell Immunity +7