Patricia B. Trusk

A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer

Wenle Xia, Sarah Bacus, Priti S. Hegde et al. · Proceedings of the National Academy of Sciences · 2006 · 377 citations · Full text

Breast Oncology, Estrogen Receptor, Pharmacotherapy +17

A reciprocal tensin-3–cten switch mediates EGF-driven mammary cell migration

Menachem Katz, Ido Amit, Ami Citri et al. · Nature Cell Biology · 2007 · 202 citations

Reciprocal Tensin-3–cten Switch, Cell-matrix Interaction, Cell Migration +5

Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes

Kimberly R. Doherty, Robert Wappel, Dominique R. Talbert et al. · Toxicology and Applied Pharmacology · 2013 · 166 citations

Cardiomyopathy, Medicine, Cardiovascular Pharmacology +8

The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity

Christina K. Baumgartner, Hakimeh Ebrahimi-Nik, Arvin Iracheta‐Vellve et al. · Nature · 2023 · 145 citations · Full text

Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells

Neil L. Spector, Yosef Yarden, Bradley L. Smith et al. · Proceedings of the National Academy of Sciences · 2007 · 117 citations · Full text

Cardiac Muscle, Heart Failure, Cell Death +18