Tim Lock

The Metabotropic Glutamate Receptor 7 Allosteric Modulator AMN082: A Monoaminergic Agent in Disguise?

Stacey J. Sukoff Rizzo, Sarah K. Leonard, A. Gilbert et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 103 citations

Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists

Julia Heinrich, John A. Butera, Tikva Carrick et al. · European Journal of Pharmacology · 2009 · 98 citations

Historical Versus, Functional Selectivity, Medicine +9

Old and New Pharmacology: Positive Allosteric Modulation of the α7 Nicotinic Acetylcholine Receptor by the 5-Hydroxytryptamine2B/C Receptor Antagonist SB-206553 (3,5-Dihydro-5-methyl-N-3-pyridinylbenzo[1,2-b:4,5-b′]di pyrrole-1(2 H)-carboxamide)

John Dunlop, Tim Lock, Brian Jow et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 65 citations

In vitro screening strategies for nicotinic receptor ligands

John Dunlop, Renza Roncarati, Brian Jow et al. · Biochemical Pharmacology · 2007 · 44 citations

Tobacco Control, Drug Target, Medicine +5

Novel Alpha-7 Nicotinic Acetylcholine Receptor Agonists Containing a Urea Moiety: Identification and Characterization of the Potent, Selective, and Orally Efficacious Agonist 1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) Urea (SEN34625/WYE-103914)

Chiara Ghiron, Simon N. Haydar, Suzan Aschmies et al. · Journal of Medicinal Chemistry · 2010 · 30 citations · Full text

Brain Penetration, Pharmacotherapy, Medicinal Chemistry +18