Jung-Hoon Pyo

Mechanism of metformin: Inhibition of DNA damage and proliferative activity in Drosophila midgut stem cell

Hyun‐Jin Na, Joung‐Sun Park, Jung-Hoon Pyo et al. · Mechanisms of Ageing and Development · 2013 · 64 citations

Cell Lineage, Dna Damage, Developmental Biology +7

Neuronal induction of BNIP3-mediated mitophagy slows systemic aging in Drosophila

Edward T. Schmid, Jung-Hoon Pyo, David W. Walker · Nature Aging · 2022 · 60 citations · Full text

Lifespan Extension, Mitophagy, Bnip3-mediated Mitophagy +10

Metformin inhibits age-related centrosome amplification in Drosophila midgut stem cells through AKT/TOR pathway

Hyun-Jin Na, Joung-Sun Park, Jung-Hoon Pyo et al. · Mechanisms of Ageing and Development · 2015 · 49 citations · Full text

Age-related Centrosome Amplification, Cell Proliferation, Cancer Biology +17

Age- and oxidative stress-induced DNA damage in Drosophila intestinal stem cells as marked by Gamma-H2AX

Joung‐Sun Park, Shin‐Hae Lee, Hyun‐Jin Na et al. · Experimental Gerontology · 2012 · 44 citations

Chromatin, Genome Instability, Dna Damage +10

Deficiency of Atg6 impairs beneficial effect of metformin on intestinal stem cell aging in Drosophila

Hyun‐Jin Na, Jung-Hoon Pyo, Ho-Jun Jeon et al. · Biochemical and Biophysical Research Communications · 2018 · 41 citations

Intestinal Stem Cell, Cell Lineage, Developmental Genetics +8