Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine.

Dai Nakae, Yuki Kobayashi, Hiroyuki Akai, +5

PubMed

Nitrosative StressRat Liver ModelPathologyPharmacotherapyDen Initiation +19

Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Eijiro Okajima, Ayumi Denda, Seiichiro Ozono, +6

PubMed

Drinking WaterUrologyChemoprevention StrategyMedicineChemopreventive Effects +9

Inhibitory Effect of Tomato Juice on Rat Urinary Bladder Carcinogenesis after <i>N</i>‐Butyl‐<i>N</i>‐(4‐hydroxybutyl)nitrosamine Initiation

Eijiro Okajima, Masahiro Tsutsumi, Seiichiro Ozono, +6

Japanese Journal of Cancer Research

Age and Organ Dependent Spontaneous Generation of Nuclear 8-Hydroxydeoxyguanosine in Male Fischer 344 Rats

Dai Nakae, Hiroyuki Akai, Hideki Kishida, +3

Laboratory Investigation

Developmental BiologyMale Fischer 344Endocrine MechanismComparative EndocrinologyMedicine +7

Implications of protein kinase C in the nucleus accumbens in the development of sensitization to methamphetamine in rats

Minoru Narita, Hiroyuki Akai, Yoko Nagumo, +6

Neuroscience

Protein Kinase CBehavioral NeuroscienceMedicinePhysiologyNeuropeptide Receptor +7

Effects of methionine and related compounds on plasma cholesterol level in rats fed a high cholesterol diet.

Kimio SUGIYAMA, Hiroyuki Akai, Keiichirô MURAMATSU

Journal of Nutritional Science and Vitaminology

Metabolic SyndromeNutritionBiochemistryMethyl CompoundsMedicine +10

Chemopreventive Efficacy of Piroxicam Administered Alone or in Combination with Lycopene and β‐Carotene on the Development of Rat Urinary Bladder Carcinoma after A <i>N</i>‐Butyl‐<i>N</i>‐(4‐hydroxybutyl)nitrosamine Treatment

E Okajima, Seiichiro Ozono, Takehiro Endo, +10

Japanese Journal of Cancer Research

Inhibition by Green Tea Extract of Diethylnitrosamine–initiated but Not Cholinedeficient, L–Amino Acid–defined Diet–associated Development of Putative Preneo–plastic, Glutathione S–Transferase Placental Form–positive Lesions in Rat Liver

Kazutoshi Tamura, Dai Nakae, Kohsuke Horiguchi, +6

Japanese Journal of Cancer Research

Inhibition of Early‐phase Exogenous and Endogenous Liver Carcinogenesis in Transgenic Rats Harboring a Rat Glutathione <i>S</i>‐Transferase Placental Form Gene

Dai Nakae, Ayumi Denda, Yozo Kobayashi, +6

Japanese Journal of Cancer Research

ACUTE TOXICITY OF STREPTOZOTOCIN IN SYRIAN HAMSTERS OF THE APA STRAIN

Jin-Soo Han, Mari Norimatsu, Yoshinori Sugawara, +5

Journal of Toxicologic Pathology

The Apa StrainMetabolic DisorderPathologyInsulin SignalingDrug Resistance +23