Hiroyuki Akai

Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine.

Dai Nakae, Yuki Kobayashi, Hiroyuki Akai et al. · PubMed · 1997 · 191 citations

Nitrosative Stress, Rat Liver Model, Pathology +21

Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Eijiro Okajima, Ayumi Denda, Seiichiro Ozono et al. · PubMed · 1998 · 133 citations

Drinking Water, Urology, Chemoprevention Strategy +11

Inhibitory Effect of Tomato Juice on Rat Urinary Bladder Carcinogenesis after <i>N</i>‐Butyl‐<i>N</i>‐(4‐hydroxybutyl)nitrosamine Initiation

Eijiro Okajima, Masahiro Tsutsumi, Seiichiro Ozono et al. · Japanese Journal of Cancer Research · 1998 · 76 citations · Full text

Age and Organ Dependent Spontaneous Generation of Nuclear 8-Hydroxydeoxyguanosine in Male Fischer 344 Rats

Dai Nakae, Hiroyuki Akai, Hideki Kishida et al. · Laboratory Investigation · 2000 · 63 citations

Developmental Biology, Male Fischer 344, Endocrine Mechanism +9

Implications of protein kinase C in the nucleus accumbens in the development of sensitization to methamphetamine in rats

Minoru Narita, Hiroyuki Akai, Yoko Nagumo et al. · Neuroscience · 2004 · 59 citations

Protein Kinase C, Behavioral Neuroscience, Medicine +9