Dennis C. Ko

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

David M. Tobin, Francisco J. Roca, Sungwhan F. Oh et al. · Cell · 2012 · 560 citations · Full text

Inflammation, Host Response, Bacterial Infections +13

Dynamic Movements of Organelles Containing Niemann-Pick C1 Protein: NPC1 Involvement in Late Endocytic Events

Dennis C. Ko, Michael D. Gordon, Janet Jin et al. · Molecular Biology of the Cell · 2001 · 243 citations

Molecular Biology, Cellular Physiology, Npc1 Organelles +17

Cell-Autonomous Death of Cerebellar Purkinje Neurons with Autophagy in Niemann-Pick Type C Disease

Dennis C. Ko, Ljiljana Milenković, Steven Beier et al. · PLoS Genetics · 2005 · 216 citations · Full text

Mitophagy, Cell Death, Npc Function +22

The integrity of a cholesterol-binding pocket in Niemann–Pick C2 protein is necessary to control lysosome cholesterol levels

Dennis C. Ko, Jonathan Binkley, Arend Sidow et al. · Proceedings of the National Academy of Sciences · 2003 · 208 citations · Full text

Binding between the Niemann–Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

Nobutaka Ohgami, Dennis C. Ko, Matthew A. M. Thomas et al. · Proceedings of the National Academy of Sciences · 2004 · 203 citations · Full text