Concepedia

Patricia N. Sidharta

PN

33

Publications

1.1K

Citations

18

H-Index

2006

Active since

Affiliations

Actelion (Switzerland)(Current)

Idorsia (Switzerland)

Clinical Research Services

Technische Hochschule Mannheim

University of Mannheim

Patricia N. Sidharta is an author at Actelion (Switzerland) specializing in pharmacology, medicine, and pharmacotherapy.

Top concepts

MedicinePharmacologyPharmacotherapyPhysiologyPharmacokineticsClinical PharmacologyHypertensionPharmacodynamic ModelingDrug DiscoveryVascular Biology

Publications per year

2006–2022

33

Publications

33

Macitentan: entry-into-humans study with a new endothelin receptor antagonist

Patricia N. Sidharta, Paul L. M. van Giersbergen, Atef Halabi et al. · European Journal of Clinical Pharmacology · 2011 · 107 citations · Full text

Setipiprant, a selective <scp>CRTH</scp>2 antagonist, reduces allergen‐induced airway responses in allergic asthmatics

Zuzana Diamant, Patricia N. Sidharta, Dave Singh et al. · Clinical & Experimental Allergy · 2014 · 83 citations

Safety, tolerability, pharmacokinetics, and pharmacodynamics of macitentan, an endothelin receptor antagonist, in an ascending multiple‐dose study in healthy subjects

Patricia N. Sidharta, Paul L. M. van Giersbergen, Jasper Dingemanse · The Journal of Clinical Pharmacology · 2013 · 77 citations

Absorption, distribution, metabolism, and excretion of macitentan, a dual endothelin receptor antagonist, in humans

Shirin Bruderer, Gérard Hopfgartner, Michael Seiberling et al. · Xenobiotica · 2012 · 76 citations

Effect of Cyclosporine and Rifampin on the Pharmacokinetics of Macitentan, a Tissue-Targeting Dual Endothelin Receptor Antagonist

Shirin Bruderer, Päivi Äänismaa, Marie‐Claude Homery et al. · The AAPS Journal · 2011 · 68 citations · Full text

Molecular Pharmacology, Hypertension, Multiple-dose Macitentan +14

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